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Mely hormon gyógyszerek (GnRHa) működnek a legjobban a petefészek-stimulációs hormonokkal együtt, az asszisztált fogamzási ciklusokban?

5 months ago
Mely hormon gyógyszerek (GnRHa) működnek a legjobban a petefészek-stimulációs hormonokkal együtt, az asszisztált fogamzási ciklusokban? Kulcsfontosságú üzenetek - A hosszú és a rövid ideig tartó gonadotropinfelszabadító hormon agonista (GnRHa) kezelés összehasonlításakor, az élveszületési és a terhességi arányok tekintetében alig volt különbség a csoportok között, de a hosszú kezelés klinikailag jobb terhességi arányt eredményezhet (amikor a magzat látható vagy hallható). - Bizonytalan, hogy van-e különbség az élveszületési és klinikai terhességi arányokban az összehasonlítások alapján,...

Cochrane seeks Administrative Assistant

5 months 3 weeks ago

Title:  Administrative Assistant
Specifications: 12 month Fixed term contract – Full Time
Salary: £27,000 per annum
Location: (Remote) based in the UK, Germany or Denmark
Directorate: Evidence Production and Methods Directorate
Closing date: 10 January, 2025

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

This role provides effective and efficient administrative support the Cochrane Evidence Production & Methods Directorate (EPMD), primarily supporting the two Deputies and three Heads of the department.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

  • An opportunity to truly impact health globally
  • A flexible work environment
  • A comprehensive onboarding experiences
  • An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values. Cochrane has offices with payroll in the UK, Germany and Denmark.

How to apply

Monday, December 23, 2024 Category: Jobs
Harry Dayantis

Cochrane seeks Senior Administrative Officer (BGESC)

5 months 3 weeks ago

Title: Senior Administrative Officer (BGESC)
Specifications: 6 month Fixed term contract – Full Time
Salary: £35, 000 per annum
Location: (Remote) based in the UK, Germany or Denmark.
Directorate: Evidence Production and Methods Directorate
Closing date: 5 January, 2025

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.
As the BGESC Senior Administrative Officer, you will be key in providing high-level administrative, organizational, and logistical support to BGESC Project Manager, BGESC leadership team (four people) and to the Co-chairs of six international working/planning groups (approximately 20 people per group including Co-chairs).

This role is essential for ensuring the smooth execution of the ‘Building a Global Evidence Synthesis Community’ initiative, within a tight timeframe. By efficiently managing administrative tasks and optimizing processes, you will enable the Project Manager and leadership team to concentrate on strategic priorities and delivering key project milestones. The BGESC Administrative Officer will also provide support to BGESC Planning Clerks and Planning Analysts (nine people), who in turn work closely with the working/planning groups Co-chairs.

The BGESC project is part of the Wellcome Trust’s wider ‘Evidence Synthesis Infrastructure Collaborative’ initiative, but the successful candidate will be a Cochrane employee.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

  • An opportunity to truly impact health globally
  • A flexible work environment
  • A comprehensive onboarding experiences
  • An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values. Cochrane has offices with payroll in the UK, Germany and Denmark.

How to apply

Monday, December 23, 2024 Category: Jobs
Harry Dayantis

Hatékonyak-e az oktatási intézményekben az önkárosító magatartások és az öngyilkosság megelőzésére hozott intézkedések a 25 év alatti tanulók esetében?

5 months 3 weeks ago
Hatékonyak-e az oktatási intézményekben az önkárosító magatartások és az öngyilkosság megelőzésére hozott intézkedések a 25 év alatti tanulók esetében? Kulcsfontosságú üzenetek - A kérdésünk megválaszolására 51 tanulmányt találtunk, de továbbra is bizonytalanok vagyunk az önkárosító magatartások csökkentését célzó, oktatási környezetben végzett beavatkozások hatásával kapcsolatban. - Vannak biztató eredmények, de ezek megerősítéséhez nagyszabású, valamint olyan tanulmányokra van szükségünk, amelyek a fiatalokkal közösen kialakított, biztonságos környezetben megvalósítható, és hosszú távon is...

Update on ‘Exercise therapy for chronic fatigue syndrome’

5 months 4 weeks ago

In 2019, Cochrane published an amended version of the review 'Exercise therapy for chronic fatigue syndrome’ and, at that time, announced an intention to further update the review. Due to insufficient new research in the field and a lack of resources to oversee this work, the update will not be proceeding.

Any feedback on this decision should follow Cochrane’s established complaints process. Any correspondence sent directly to individuals at Cochrane will not be considered.

Monday, December 16, 2024
Harry Dayantis

£10 million global consortium to advance evidence synthesis in climate and health

6 months 1 week ago

Cochrane is part of a new global consortium to develop new tools, powered by artificial intelligence (AI), to analyse and synthesise research evidence on the relationships between climate change and human health.

The consortium is supported by a £10.2 million grant from Wellcome over four years, led by the Berlin-based climate research institute MCC.

The DESTINY project will develop novel AI-driven tools to make evidence synthesis faster, more efficient and continuously updated. The tools aim to automate and streamline tasks such as detecting relevant individual studies, extracting and synthesising their respective findings and identifying overarching insights.

As an internationally-recognised leader in evidence synthesis for human health, Cochrane will help to apply our methodological expertise to the field of climate research. We will co-lead several work programmes with the Campbell Collaboration, who specialize in evidence synthesis for social research.

It will be vital to ensure that outputs from automated tools are responsible and robust, with human oversight offering safeguards and methodological expertise. Cochrane will co-lead this workstream with Campbell, defining standards for responsible AI use and producing best-practice guidance. We will also help to ensure that the technology can be used equitably across the world, working with our extensive global network and consortium partners to build and strengthen capacity.

“Climate change poses one of the greatest threats to human health, so this project is both vital and timely,” says Dr Karla Soares-Weiser, Editor-in-Chief of the Cochrane Library and co-Principal Investigator on the DESTINY project. “It has the potential to transform evidence synthesis for climate and health, equipping decision-makers with the evidence they need to make informed decisions. Climate change is a key research priority in Cochrane’s scientific strategy, while methodological innovation is one of our core commitments. The DESTINY project will enable us to further these goals in collaboration with partners across the world, all bringing our own strengths to deliver the best outcomes.”

The project takes place in the context of a wider investment into evidence synthesis infrastructure, with £54.2 million of funding announced in September from both Wellcome and the UK government. The DESTINY grant is a separate award focused on climate change and health, signalling Wellcome’s leadership in this area.

“Stopping climate change is critical for securing human health,” says Jan Minx, head of the MCC working group Applied Sustainability Science and principal investigator of the DESTINY project. “Policymakers need the best and most recent scientific evidence to support their decisions, but the ready-to-hand evidence is often anecdotal and outdated. This project is pushing the boundaries of what is possible by using the latest advances in AI. It will demonstrate that the scientific knowledge needed for health-centred climate action can be synthesised and provided almost instantly. Speed and scientific rigour can go hand in hand – this is key to efficiently solving the big issues of our time.”

The consortium partners are Cochrane, University College London, The London School of Hygiene & Tropical Medicine, the ACRES Center for Rapid Evidence Synthesis, Future Evidence Foundation, the African Synthesis Centre for Climate Change, Environment and Development, Effective Basic Services (eBase) Africa, the Campbell Collaboration. “Having a diverse community of partners will ensure equity and inclusion in global evidence infrastructures,” says Patrick Okwen, Co-Investigator from eBase Africa.

Friday, December 6, 2024
Harry Dayantis

Cochrane seeks Assistant Quality Assurance Editor

6 months 1 week ago

Title: Assistant Quality Assurance Editor
Specifications: Permanent – Full Time
Salary: £30,000 per annum
Location: (Remote) based in the UK, Germany or Denmark
Directorate: Evidence Production and Methods Directorate
Closing date: 17 December 2024

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

As Assistant Quality Assurance Editor within Cochrane’s Editorial Department, you will provide support to the Quality Assurance Editor and Senior Quality Assurance Editor, to help them to assess whether protocols, reviews and updates submitted to Cochrane’s Central Editorial Service have met Cochrane’s methodological standards. The post holder will provide this support by gathering information on individual reviews (e.g., by performing initial checks on submitted reviews, identifying and accessing relevant papers, or performing consistency checks within the reviews), assisting with the write up of peer review reports, and helping the Quality Assurance Team to reach consensus on recommendations to make for each submission.

You will also be trained to conduct your own full assessments of protocols, reviews and updates submitted to Cochrane’s Central Editorial Service have met Cochrane’s methodological standards, with the possibility of moving up a level to the role of ‘Quality Assurance Editor’ at a future stage. 

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organisation is built on four core values:

Collaboration: Underpins everything we do, locally and globally.

Relevant: The right evidence at the right time in the right format.

Integrity: Independent and transparent.

Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

  • An opportunity to truly impact health globally.
  •   A flexible work environment
  • A comprehensive onboarding experiences.
  •  An environment where people feel welcome, heard, and included, regardless of their differences.

Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  •  For further information on the role and click “how to apply”.
  • The deadline to receive your application is 17 December, 2024.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
  • Read our Recruitment Privacy Statement
Thursday, December 5, 2024 Category: Jobs
Mia Parkinson

Melyik kemoterápiás kezelés a legjobb az előrehaladott hasnyálmirigyrákban szenvedő betegek számára?

6 months 1 week ago
Melyik kemoterápiás kezelés a legjobb az előrehaladott hasnyálmirigyrákban szenvedő betegek számára? Kulcsfontosságú üzenetek - A FOLFIRINOX és a gemcitabin/taxán kombinációs kezelés meghosszabbítja az előrehaladott hasnyálmirigyrákban szenvedő betegek életét a csak gemcitabint alkalmazó kezeléshez képest. - Eredményeink arra utalnak, hogy a fluoropirimidin alapú kombinált kemoterápia meghosszabbítja az előrehaladott hasnyálmirigyrákban szenvedő betegek életét a gemcitabin/taxán kezeléshez képest. Mi a hasnyálmirigyrák? A hasnyálmirigyrák egy rendkívül agresszív daganatos megbetegedés,...

Segíthetnek-e kötszerek, krémek vagy olajok a fekélyek megelőzésében?

6 months 1 week ago
Segíthetnek-e kötszerek, krémek vagy olajok a fekélyek megelőzésében? Kulcsfontosságú üzenetek Az általunk azonosított bizonyítékok bizonytalan jellege azt jelenti, hogy nem tudjuk, hogy a kötszerek vagy a helyi kezelés (beleértve a különböző krémeket, testápolókat és olajokat) befolyásolják-e a kockázati csoportba tartozóknál a kialakuló fekélyek számát. Mi az a fekély? A fekélyek, vagy más néven nyomási sérülések a bőr vagy az alatta lévő szövetek a test csontos területeire gyakorolt hosszan tartó nyomása következtében keletkeznek. Gyakoriak az idős és korlátozott mozgásképességű egyének...

Hatékony terápia-e a testmozgás térdízületi kopás kezelésére?

6 months 1 week ago
Hatékony terápia-e a testmozgás térdízületi kopás kezelésére? Kulcsüzenetek - A testmozgás javulást eredményezhet a fájdalom és a fizikai funkció terén a „megfigyelt” kontrollhoz (azaz a kutatócsoporttal vagy az ellátó személyzettel való több mint egy interakciót magába foglaló kontrollhoz) vagy placebóhoz képest, valamint javulást a fájdalom, a fizikai funkció és az életminőség terén a kezelés hiányához, a szokásos ellátáshoz (pl. a háziorvos által kínált rutin kezelés) vagy a korlátozott oktatáshoz (pl. egy alapvető tájékoztató brosúra vagy online információhoz vezető link biztosítása)...